Shared polygenic risk and causal inferences in Parkinson's disease

Modifiable factors play a key role in modulating the risk of Parkinson's disease (PD). We performed a two-stage genetic analyses to explore genetic correlations and causal relationships between modifiable factors and PD risk. The exposures consisted of GWAS summary statistics of 516 modifiable...

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Bibliographic Details
Main Authors: Rui-Qi Zhang, Kevin Kuo, Feng-Tao Liu, Shi-Dong Chen, Yu-Xiang Yang, Yu Guo, Qiang Dong, Lan Tan, Can Zhang, Jin-Tai Yu
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Brain Disorders
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666459322000191