Active Targeting of P-Selectin by Fucoidan Modulates the Molecular Profiling of Metastasis in Docetaxel-Resistant Prostate Cancer

Active Targeting of P-Selectin by Fucoidan Modulates the Molecular Profiling of Metastasis in Docetaxel-Resistant Prostate Cancer

The standard of care for prostate cancer (PCa) is androgen deprivation therapy (ADT). Although hormone-sensitive PCa is curable by ADT, most conditions progress to castration-resistant prostate cancer (CRPCa) and metastatic CRPCa (mCRPCa). Front-line docetaxel has been administered to patients with...

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Bibliographic Details
Main Authors: Chang-Hsun Ho, Mei-Lin Chen, Hau-Lun Huang, Chih-Jen Lai, Chih-Hsin Liu, Chih-Pin Chuu, Yu-Hsin Lin
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Marine Drugs
Subjects:
prostate cancer
docetaxel resistant
fucoidan
metastasis-inhibiting signaling pathway
synergistic effects
Online Access:https://www.mdpi.com/1660-3397/20/9/542

Internet

https://www.mdpi.com/1660-3397/20/9/542

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