Substrate-Dependent <i>Trans</i>-Stimulation of Organic Cation Transporter 2 Activity

The search of substrates for solute carriers (SLCs) constitutes a major issue, owing notably to the role played by some SLCs, such as the renal electrogenic organic cation transporter (OCT) 2 (<i>SLC22A2</i>), in pharmacokinetics, drug–drug interactions and drug toxicity. For this purpos...

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Bibliographic Details
Main Authors: Charles R. Lefèvre, Marc Le Vée, Sophie Gaubert, Elodie Jouan, Arnaud Bruyere, Caroline Moreau, Olivier Fardel
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/23/12926