Identification and characterization of PKF118-310 as a KDM4A inhibitor

Epigenetic modifications are functionally involved in gene expression regulation. In particular, histone posttranslational modifications play a crucial role in functional chromatin organization. Several drugs able to inhibit or stimulate some families of proteins involved in epigenetic histone regul...

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Bibliographic Details
Main Authors: Gianluigi Franci, Federica Sarno, Angela Nebbioso, Lucia Altucci
Format: Article
Language:English
Published: Taylor & Francis Group 2017-03-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2016.1249089