A Novel TBK1 Variant (Lys694del) Presenting With Corticobasal Syndrome in a Family With FTD-ALS Spectrum Diseases: Case Report

A Novel TBK1 Variant (Lys694del) Presenting With Corticobasal Syndrome in a Family With FTD-ALS Spectrum Diseases: Case Report

Several variants of the TANK-Binding Kinase 1 (TBK1) gene have been associated with frontotemporal dementia - amyotrophic lateral sclerosis (FTD-ALS) spectrum diseases. Corticobasal syndrome (CBS) is characterized by asymmetric limb rigidity, dystonia or myoclonus, in association with speech or limb...

Full description

Bibliographic Details
Main Authors: Kaitlin Seibert, Heather Smith, Allison Lapins, Peter Pytel, James A. Mastrianni
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neurology
Subjects:
frontotemporal dementia
corticobasal syndrome
TBK1
motor neuron disease
dementia
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.826676/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.826676/full

Similar Items