LGR6 is a prognostic biomarker for less differentiated tumors in lymph nodes of colon cancer patients

LGR6 is a prognostic biomarker for less differentiated tumors in lymph nodes of colon cancer patients

IntroductionThe aim was to investigate whether the stem cell marker LGR6 has prognostic value in colon cancer, alone or in combination with the prognostic biomarkers CEA and CXCL16.MethodsLGR6 mRNA levels were determined in 370 half lymph nodes of 121 colon cancer patients. Ability to predict relaps...

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Bibliographic Details
Main Authors: Hagar Eltorky, Manar AbdelMageed, Hager Ismail, Faten Zahran, Adel Guirgis, Lina Olsson, Gudrun Lindmark, Marie-Louise Hammarström, Sten Hammarström, Basel Sitohy
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Oncology
Subjects:
colon cancer
regional lymph nodes
cancer stem cells
LGR6
LGR5
CEA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1393075/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1393075/full

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