Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence

Development of the dorsal aorta is a key step in the establishment of the adult blood-forming system, since hematopoietic stem and progenitor cells (HSPCs) arise from ventral aortic endothelium in all vertebrate animals studied. Work in zebrafish has demonstrated that arterial and venous endothelial...

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Bibliographic Details
Main Authors: Pankaj Sahai-Hernandez, Claire Pouget, Shai Eyal, Ondrej Svoboda, Jose Chacon, Lin Grimm, Tor Gjøen, David Traver
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/58300