Next-generation sequencing-based analysis of homologous recombination repair gene variant in ovarian cancer

Next-generation sequencing-based analysis of homologous recombination repair gene variant in ovarian cancer

Background: Ovarian cancer is the leading cause of death from gynecological malignancies. Investigating the HRR-related gene status, notably BRCA1/2 in different regions and populations is of great significance for formulating accurate target therapy. Methods: We collected 124 ovarian cancer cases f...

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Bibliographic Details
Main Authors: Yaolin Song, Wenwen Ran, Huiqing Jia, Qin Yao, Guangqi Li, Yang Chen, Xiaonan Wang, Yujing Xiao, Mengqi Sun, Xiao Lu, Xiaoming Xing
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Homologous recombination repair
BRCA1/2 mutation
Next
Generation sequencing
Ovarian cancer
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023108929

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http://www.sciencedirect.com/science/article/pii/S2405844023108929

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