AMP-activated protein kinase promotes breast cancer stemness and drug resistance

AMP-activated protein kinase promotes breast cancer stemness and drug resistance

Breast cancer stem cells (BCSCs) are a major cause of therapy resistance and tumour progression. Currently, their regulation is not entirely understood. Previous work from our laboratory demonstrated a context-specific pro-tumorigenic role for AMP-activated protein kinase (AMPK) under anchorage-depr...

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Bibliographic Details
Main Authors: Sai Balaji Andugulapati, Ananthalakshmy Sundararaman, Mohini Lahiry, Annapoorni Rangarajan
Format: Article
Language:English
Published: The Company of Biologists 2022-06-01
Series:Disease Models & Mechanisms
Subjects:
ampk
anchorage deprivation
stemness
drug resistance
twist
Online Access:http://dmm.biologists.org/content/15/6/dmm049203

Internet

http://dmm.biologists.org/content/15/6/dmm049203

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