Potential pharmacokinetic interactions in fixed-dose combinations of perindopril/indapamide/amlodipine compared with perindopril/indapamide and amlodipine in healthy Chinese volunteers

Potential pharmacokinetic interactions in fixed-dose combinations of perindopril/indapamide/amlodipine compared with perindopril/indapamide and amlodipine in healthy Chinese volunteers

S05590 is a fixed-dose combination of perindopril tert-butylamine 4 mg/indapamide 1.25 mg, and S06593 is a fixed-dose combination of perindopril arginine 5 mg/indapamide 1.25 mg/amlodipine 5 mg. The purpose of this study was to determine whether pharmacokinetic interactions exist among the component...

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Bibliographic Details
Main Authors: Huitao Gao, Hongzhong Liu, Xin Zheng, Xinge Cui, Stephanie Bricout-Hennel, Arnaud Lucien, Pauline Lauruol, Yaqin Wang, Xue Wang, Hongyun Wang, Chen Rui
Format: Article
Language:English
Published: Compuscript Ltd 2023-03-01
Series:Acta Materia Medica
Subjects:
perindopril
indapamide
amlodipine
pharmacokinetic interaction
safety
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2022-0045

Internet

https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2022-0045

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