Somatic mutations in tumor and plasma of locoregional recurrent and/or metastatic head and neck cancer using a next‐generation sequencing panel: A preliminary study

Somatic mutations in tumor and plasma of locoregional recurrent and/or metastatic head and neck cancer using a next‐generation sequencing panel: A preliminary study

Abstract Background We explore the utility of TruSight Tumor 170 panel (TST170) for detecting somatic mutations in tumor and cfDNA from locoregional recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC). Methods Targeted NGS of tumor DNA and plasma cfDNA was performed using TST17...

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Bibliographic Details
Main Authors: Óscar Rapado‐González, Jenifer Brea‐Iglesias, Aitor Rodríguez‐Casanova, Aida Bao‐Caamano, José‐Luis López‐Cedrún, Gabriel Triana‐Martínez, Roberto Díaz‐Peña, María Arminda Santos, Rafael López‐López, Laura Muinelo‐Romay, Mónica Martínez‐Fernández, Ángel Díaz‐Lagares, María Mercedes Suárez‐Cunqueiro
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Cancer Medicine
Subjects:
cell‐free DNA
droplet digital PCR
head and neck squamous cell carcinoma
liquid biopsy
next‐generation sequencing
saliva
Online Access:https://doi.org/10.1002/cam4.5436

Internet

https://doi.org/10.1002/cam4.5436

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