Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity

β-Sitosterol (β-Sit) is a dietary phytosterol with demonstrated anticancer activity against a panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic efficacy. In this study, poly(lactide-co-glycolic acid) (PLGA) and block copolymers of poly(et...

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Những tác giả chính: Moses Andima, Gabriella Costabile, Lorenz Isert, Albert J. Ndakala, Solomon Derese, Olivia M. Merkel
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2018-11-01
Loạt:Pharmaceutics
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Truy cập trực tuyến:https://www.mdpi.com/1999-4923/10/4/232