Genome-wide inference of ancestral recombination graphs.

The complex correlation structure of a collection of orthologous DNA sequences is uniquely captured by the "ancestral recombination graph" (ARG), a complete record of coalescence and recombination events in the history of the sample. However, existing methods for ARG inference are computat...

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Bibliographic Details
Main Authors: Matthew D Rasmussen, Melissa J Hubisz, Ilan Gronau, Adam Siepel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4022496?pdf=render