Biotinylated Bilirubin Nanoparticles as a Tumor Microenvironment‐Responsive Drug Delivery System for Targeted Cancer Therapy

Biotinylated Bilirubin Nanoparticles as a Tumor Microenvironment‐Responsive Drug Delivery System for Targeted Cancer Therapy

Abstract The tumor microenvironment (TME) plays a crucial role in tumorigenesis and cancer cell metastasis. Accordingly, a drug‐delivery system (DDS) that is capable of targeting tumor and releasing drugs in response to TME‐associated stimuli should lead to potent antitumor efficacy. Here, a cancer...

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Bibliographic Details
Main Authors: Yonghyun Lee, Soyoung Lee, Sangyong Jon
Format: Article
Language:English
Published: Wiley 2018-06-01
Series:Advanced Science
Subjects:
bilirubin nanoparticles
biotin transporters
reactive oxygen species (ROS)
stimuli responsiveness
targeted cancer therapy
tumor microenvironments
Online Access:https://doi.org/10.1002/advs.201800017

Internet

https://doi.org/10.1002/advs.201800017

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