The Role of the CoREST/REST Repressor Complex in Herpes Simplex Virus 1 Productive Infection and in Latency

REST is a key component of the HDAC1 or 2, CoREST, LSD1, REST (HCLR) repressor complex. The primary function of the HCLR complex is to silence neuronal genes in non-neuronal cells. HCLR plays a role in regulating the expression of viral genes in productive infections as a donor of LDS1 for expressio...

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Bibliographic Details
Main Authors: Bernard Roizman, Te Du, Guoying Zhou
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/5/5/1208