Theoretical analysis of the stress induced B-Z transition in superhelical DNA.
We present a method to calculate the propensities of regions within a DNA molecule to transition from B-form to Z-form under negative superhelical stresses. We use statistical mechanics to analyze the competition that occurs among all susceptible Z-forming regions at thermodynamic equilibrium in a s...
| Hoofdauteurs: | , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2011-01-01
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| Reeks: | PLoS Computational Biology |
| Online toegang: | http://europepmc.org/articles/PMC3024258?pdf=render |