Electroacupuncture alleviates orofacial allodynia and anxiety-like behaviors by regulating synaptic plasticity of the CA1 hippocampal region in a mouse model of trigeminal neuralgia

Electroacupuncture alleviates orofacial allodynia and anxiety-like behaviors by regulating synaptic plasticity of the CA1 hippocampal region in a mouse model of trigeminal neuralgia

ObjectiveTrigeminal neuralgia (TN), one of the most severe and debilitating chronic pain conditions, is often accompanied by mood disorders, such as anxiety and depression. Electroacupuncture (EA) is a characteristic therapy of Traditional Chinese Medicine with analgesic and anxiolytic effects. This...

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Bibliographic Details
Main Authors: Yu-Zhi Jia, Hai-Tao Li, Guang-Ming Zhang, Hong-Yun Wu, Si-Shuo Zhang, Hong-Wei Zhi, Ya-Han Wang, Jing-Wen Zhu, Yi-Fan Wang, Xiang-Qing Xu, Cai-Jun Tian, Wen-Qiang Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
trigeminal neuralgia
anxiety
electroacupuncture
synaptic plasticity
hippocampal CA1 region
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.979483/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2022.979483/full

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