The protective effect of rutin and quercetin on 5-FU-induced hepatotoxicity in rats

Objective: To investigate the effects of quercetin (Q) and rutin on 5-fluorouracil (5-FU)-induced hepatotoxicity. Methods: The control group was corn oil. The 5-FU group rats were corn oil and injected intraperitoneal 5-FU 50 mg/kg. Groups rutin 50 + 5-FU and rutin 100 + 5-FU were respectively 50 mg...

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Bibliographic Details
Main Authors: Volkan Gelen, Emin Şengül, Semin Gedikli, Gözde Atila, Hamit Uslu, Mustafa Makav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-07-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169117305762