Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.

The phenotypic characterization of the cells in which HIV persists during antiretroviral therapy (ART) remains technically challenging. We developed a simple flow cytometry-based assay to quantify and characterize infected cells producing HIV proteins during untreated and treated HIV infection. By c...

Full description

Bibliographic Details
Main Authors: Marion Pardons, Amy E Baxter, Marta Massanella, Amélie Pagliuzza, Rémi Fromentin, Caroline Dufour, Louise Leyre, Jean-Pierre Routy, Daniel E Kaufmann, Nicolas Chomont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6411230?pdf=render

Internet

http://europepmc.org/articles/PMC6411230?pdf=render

Similar Items