Exercise mitigates Dapagliflozin-induced skeletal muscle atrophy in STZ-induced diabetic rats

Exercise mitigates Dapagliflozin-induced skeletal muscle atrophy in STZ-induced diabetic rats

Abstract Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are commonly used in the management of type 2 diabetes mellitus (T2DM) and have been found to worsen the reduction of skeletal muscle mass in individuals with T2DM. This study aims to examine the potential of exercise in mitigati...

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Bibliographic Details
Main Authors: Xudong Yang, Lifeng Wang, Liangzhi Zhang, Xia Zhai, Xiusheng Sheng, Helong Quan, Hengjun Lin
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Dapagliflozin
Exercise
Type 2 diabetes
SGLT2 inhibitors
Skeletal muscle atrophy
Protein metabolism
Online Access:https://doi.org/10.1186/s13098-023-01130-w

Internet

https://doi.org/10.1186/s13098-023-01130-w

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