Vγ4 T Cells Inhibit the Pro-healing Functions of Dendritic Epidermal T Cells to Delay Skin Wound Closure Through IL-17A

Vγ4 T Cells Inhibit the Pro-healing Functions of Dendritic Epidermal T Cells to Delay Skin Wound Closure Through IL-17A

Dendritic epidermal T cells (DETCs) and dermal Vγ4 T cells engage in wound re-epithelialization and skin inflammation. However, it remains unknown whether a functional link between Vγ4 T cell pro-inflammation and DETC pro-healing exists to affect the outcome of skin wound closure. Here, we revealed...

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Bibliographic Details
Main Authors: Yashu Li, Yangping Wang, Lina Zhou, Meixi Liu, Guangping Liang, Rongshuai Yan, Yufeng Jiang, Jianlei Hao, Xiaorong Zhang, Xiaohong Hu, Yong Huang, Rupeng Wang, Zhinan Yin, Jun Wu, Gaoxing Luo, Weifeng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
wound healing
Vγ4 T cells
dendritic epidermal T cells
IL-17A
IL-1β
IL-23
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00240/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00240/full

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