Decoding the annulus fibrosus cell atlas by scRNA-seq to develop an inducible composite hydrogel: A novel strategy for disc reconstruction

Decoding the annulus fibrosus cell atlas by scRNA-seq to develop an inducible composite hydrogel: A novel strategy for disc reconstruction

Low back pain is one of the most serious public health problems worldwide and the major clinical manifestation of intervertebral disc degeneration (IVDD). The key pathological change during IVDD is dysfunction of the annulus fibrosus (AF). However, due to the lack of an in-depth understanding of AF...

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Bibliographic Details
Main Authors: Han Wang, Di Wang, Beier Luo, Dong Wang, Haoruo Jia, Pandi Peng, Qiliang Shang, Jianxin Mao, Chu Gao, Ye Peng, Lu Gan, Junjie Du, Zhuojing Luo, Liu Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-08-01
Series:Bioactive Materials
Subjects:
Single cell RNA-Seq
Annulus fibrosus-derived stem cells
Lineage tracing
Composite hydrogel
Annulus fibrosus reconstruction
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22000482

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http://www.sciencedirect.com/science/article/pii/S2452199X22000482

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