Proteins comparison through probabilistic optimal structure local alignment

Multiple local structure comparison helps to identify common structural motifs or conserved binding sites in 3D structures of distantly related proteins. Since there is not a best way to compare structures and evaluate the alignment, a wide variety of techniques and different similarity scoring sche...

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Bibliographic Details
Main Authors: Giovanni eMicale, Alfredo ePulvirenti, Rosalba eGiugno, Alfredo eFerro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00302/full