Relationship between the Ki67 index and its area based approximation in breast cancer

Abstract Background The Ki67 Index has been extensively studied as a prognostic biomarker in breast cancer. However, its clinical adoption is largely hampered by the lack of a standardized method to assess Ki67 that limits inter-laboratory reproducibility. It is important to standardize the computat...

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Bibliographic Details
Main Authors: Muhammad Khalid Khan Niazi, Caglar Senaras, Michael Pennell, Vidya Arole, Gary Tozbikian, Metin N. Gurcan
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4735-5