The Impact of SGLT1 Inhibition on Frailty and Sarcopenia: A Mediation Mendelian Randomization Study

ABSTRACT Background Although pharmacological effects of SGLT2 inhibitors on the development of frailty and sarcopenia were known, the role of SGLT1 remained less clear. The present study investigated the possible effect of SGLT1 inhibition on these conditions and explored potential mediators. Method...

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Bibliographic Details
Main Authors: Bang‐Bang Huang, Yu‐Jie Zhang, Guang‐Feng Ruan, Xing Yu, Qin Liu, Mei‐Jin Zhang, Ming‐Zhong Yu, Ai Chen, Ye‐Bei Liang, Liang‐Di Xie, Li Luo
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.13614