An intracellular arrangement of Histoplasma capsulatum yeast-aggregates generates nuclear damage to the cultured murine alveolar macrophages

An intracellular arrangement of Histoplasma capsulatum yeast-aggregates generates nuclear damage to the cultured murine alveolar macrophages

Histoplasma capsulatum is responsible for a human systemic mycosis that primarily affects lung tissue. Macrophages are the major effector cells in humans that respond to the fungus, and the development of respiratory disease depends on the ability of Histoplasma yeast cells to survive and replicate...

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Bibliographic Details
Main Authors: Nayla De Souza Pitangui, Janaina De Cássia Orlandi Sardi, Aline Raquel eVoltan, Claudia Tavares edos Santos, Julhiany De Fátima Da Silva, Rosângela Aparecida Moraes da Silva, Felipe Oliveira Souza, Christiane Pienna Soares, Gabriela eRodríguez-Arellanes, Maria Lúcia Taylor, Maria José Soares Mendes-Giannini, Ana Marisa eFusco-Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Microbiology
Subjects:
Host-Pathogen Interactions
Histoplasma capsulatum
nucleus
alveolar macrophages
intracellular arrangement
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01526/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01526/full

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