Predicting tumour content of liquid biopsies from cell-free DNA

Predicting tumour content of liquid biopsies from cell-free DNA

Abstract Background Liquid biopsy is a minimally-invasive method of sampling bodily fluids, capable of revealing evidence of cancer. The distribution of cell-free DNA (cfDNA) fragment lengths has been shown to differ between healthy subjects and cancer patients, whereby the distributional shift corr...

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Bibliographic Details
Main Authors: Mathias Cardner, Francesco Marass, Erika Gedvilaite, Julie L. Yang, Dana W. Y. Tsui, Niko Beerenwinkel
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Bioinformatics
Subjects:
Liquid biopsy
Tumour content
Cell-free DNA
Circulating tumour DNA
Fragmentomics
Online Access:https://doi.org/10.1186/s12859-023-05478-8

Internet

https://doi.org/10.1186/s12859-023-05478-8

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