S100A8/A9 predicts response to PIM kinase and PD-1/PD-L1 inhibition in triple-negative breast cancer mouse models

S100A8/A9 predicts response to PIM kinase and PD-1/PD-L1 inhibition in triple-negative breast cancer mouse models

Abstract Background Understanding why some triple-negative breast cancer (TNBC) patients respond poorly to existing therapies while others respond well remains a challenge. This study aims to understand the potential underlying mechanisms distinguishing early-stage TNBC tumors that respond to clinic...

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Bibliographic Details
Main Authors: Lauren R. Begg, Adrienne M. Orriols, Markella Zannikou, Chen Yeh, Pranathi Vadlamani, Deepak Kanojia, Rosemary Bolin, Sara F. Dunne, Sanjeev Balakrishnan, Roman Camarda, Diane Roth, Nicolette A. Zielinski-Mozny, Christina Yau, Athanassios Vassilopoulos, Tzu-Hsuan Huang, Kwang-Youn A. Kim, Dai Horiuchi
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00444-8

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https://doi.org/10.1038/s43856-024-00444-8

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