L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas

<p>Abstract</p> <p>Wide-spread hypomethylation of CpG dinucleotides is characteristic of many cancers. Retrotransposons have been identified as potential targets of hypomethylation during cellular transformation. We report the results of an preliminary examination of the methylatio...

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Bibliographic Details
Main Authors: McDonald John F, Benigno Benedict B, Menendez Laura
Format: Article
Language:English
Published: BMC 2004-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/3/1/12