Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling

Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling

Osteoarthritis (OA) is an age-related degenerative disease characterized by cartilage degeneration and abnormal bone remodeling in the subchondral bone. Autophagy maintains cellular homeostasis by self-phagocytosis. However, the underlying mechanisms of autophagy on the pathological progression of O...

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Bibliographic Details
Main Authors: Jiangbo Yan, Gangning Feng, Yong Yang, Dong Ding, Long Ma, Xin Zhao, Xiaolei Chen, Hui Wang, Zhirong Chen, Qunhua Jin
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-01-01
Series:Biomolecules & Biomedicine
Subjects:
Osteoarthritis
chondrocyte
autophagy
pyroptosis
subchondral bone
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/7677

Internet

https://www.bjbms.org/ojs/index.php/bjbms/article/view/7677

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