Effect of paternal aging and vitrification on mitochondrial DNA copy number and telomere length of mouse blastocysts

In this study, we examined the effects of paternal aging on the mitochondrial DNA copy number (mt-cn), telomere length (TL), and gene expression in mouse embryos. The effects of vitrification on the mt-cn and TL of the embryos derived from young and aged male parents (YF and AF, respectively) were e...

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Dettagli Bibliografici
Autori principali: Nao ABURADA, Jun ITO, Yuki INOUE, Taiyo YAMAMOTO, Masamune HAYASHI, Noko TERAMOTO, Yuri OKADA, Yuichi KOSHIISHI, Koumei SHIRASUNA, Hisataka IWATA
Natura: Articolo
Lingua:English
Pubblicazione: The Society for Reproduction and Development 2024-01-01
Serie:The Journal of Reproduction and Development
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Accesso online:https://www.jstage.jst.go.jp/article/jrd/70/2/70_2023-079/_pdf/-char/en