Deep Learning-Based Pan-Cancer Classification Model Reveals Tissue-of-Origin Specific Gene Expression Signatures

Deep Learning-Based Pan-Cancer Classification Model Reveals Tissue-of-Origin Specific Gene Expression Signatures

Cancer tissue-of-origin specific biomarkers are needed for effective diagnosis, monitoring, and treatment of cancers. In this study, we analyzed transcriptomics data from 37 cancer types provided by The Cancer Genome Atlas (TCGA) to identify cancer tissue-of-origin specific gene expression signature...

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Bibliographic Details
Main Authors: Mayur Divate, Aayush Tyagi, Derek J. Richard, Prathosh A. Prasad, Harsha Gowda, Shivashankar H. Nagaraj
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
deep learning
pan cancer
cancer type prediction
gene expression signatures
Online Access:https://www.mdpi.com/2072-6694/14/5/1185

Internet

https://www.mdpi.com/2072-6694/14/5/1185

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