Improving the safety of cell therapy with the TK-suicide gene

Improving the safety of cell therapy with the TK-suicide gene

While opening new frontiers for the cure of malignant and non-malignant diseases, the increasing use of cell therapy poses also several new challenges related to the safety of a living drug. The most effective and consolidated cell therapy approach is allogeneic haematopoietic stem cell transplantat...

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Bibliographic Details
Main Authors: Raffaella eGreco, Giacomo eOliveira, Maria Teresa eLupo Stanghellini, Luca eVago, Attilio eBondanza, Jacopo ePeccatori, Nicoletta eCieri, Sarah eMarktel, Sara eMastaglio, Claudio eBordignon, Chiara eBonini, Fabio eCiceri
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Pharmacology
Subjects:
Gene Therapy
suicide gene therapy
Allogeneic haematopoietic stem cell transplantation
cellular adoptive immunotherapy
TK cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00095/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00095/full

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