Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions

Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions

Metformin is a metabolic disruptor, and its efficacy and effects on metabolic profiles under different oxygen and nutrient conditions remain unclear. Therefore, the present study examined the effects of metformin on cell growth, the metabolic activities and consumption of glucose, glutamine, and pyr...

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Bibliographic Details
Main Authors: Shan Liu, Jumpei Washio, Satoko Sato, Yuki Abiko, Yuta Shinohara, Yuri Kobayashi, Haruki Otani, Shiori Sasaki, Xiaoyi Wang, Nobuhiro Takahashi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
metformin
hypoxia
nutrient availability
rewired metabolic activity
oral cancer
dentistry
Online Access:https://www.mdpi.com/1422-0067/23/2/989

Internet

https://www.mdpi.com/1422-0067/23/2/989

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