Dynamic Compression Promotes the Matrix Synthesis of Nucleus Pulposus Cells Through Up-Regulating N-CDH Expression in a Perfusion Bioreactor Culture

Dynamic Compression Promotes the Matrix Synthesis of Nucleus Pulposus Cells Through Up-Regulating N-CDH Expression in a Perfusion Bioreactor Culture

Background/Aims: An adequate matrix production of nucleus pulposus (NP) cells is an important tissue engineering-based strategy to regenerate degenerative discs. Here, we mainly aimed to investigate the effects and mechanism of mechanical compression (i.e., static compression vs. dynamic compression...

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Bibliographic Details
Main Authors: Yichun Xu, Hui Yao, Pei Li, Wenbin Xu, Junbin Zhang, Lulu Lv, Haijun Teng, Zhiliang Guo, Huiqing Zhao, Gang Hou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Nucleus pulposus
Dynamic
Static
Compression
Matrix
Regeneration
Online Access:https://www.karger.com/Article/FullText/488616

Internet

https://www.karger.com/Article/FullText/488616

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