Overexpressed Pseudogene HLA-DPB2 Promotes Tumor Immune Infiltrates by Regulating HLA-DPB1 and Indicates a Better Prognosis in Breast Cancer

Overexpressed Pseudogene HLA-DPB2 Promotes Tumor Immune Infiltrates by Regulating HLA-DPB1 and Indicates a Better Prognosis in Breast Cancer

Immune checkpoint inhibitors (ICIs) have been successfully used for treating melanoma and non-small cell lung cancer. However, many patients with breast cancer (BC) show low response to ICIs due to the paucity of infiltrating immune cells. Pseudogenes, as a particular kind of long-chain noncoding RN...

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Bibliographic Details
Main Authors: Lijuan Lyu, Jia Yao, Meng Wang, Yi Zheng, Peng Xu, Shuqian Wang, Dai Zhang, Yujiao Deng, Ying Wu, Si Yang, Jun Lyu, Feng Guan, Zhijun Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
pseudogene
HLA-DPB2
HLA-DPB1
breast cancer
prognosis
immune infiltration
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01245/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01245/full

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