Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA.

How tightly packed chromatin is thoroughly inspected for DNA damage is one of the fundamental unanswered questions in biology. In particular, the effective excision of carcinogenic lesions caused by the ultraviolet (UV) radiation of sunlight depends on UV-damaged DNA-binding protein (UV-DDB), but th...

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Bibliographic Details
Main Authors: Jia Fei, Nina Kaczmarek, Andreas Luch, Andreas Glas, Thomas Carell, Hanspeter Naegeli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3201922?pdf=render