Plasma homocysteine and cerebral small vessel disease as possible mediators between kidney and cognitive functions in patients with diabetes mellitus

Plasma homocysteine and cerebral small vessel disease as possible mediators between kidney and cognitive functions in patients with diabetes mellitus

Abstract Cognitive impairment is more prevalent in those with decreased kidney function. We tested a hypothesis that an increased homocysteine and/or cerebral small vessel diseases (SVDs) mediate the link between kidney and cognitive functions in a cross-sectional study in 143 type 2 diabetes patien...

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Bibliographic Details
Main Authors: Mika Sonoda, Tetsuo Shoji, Yukinobu Kuwamura, Yujiro Okute, Toshihide Naganuma, Hideaki Shima, Koka Motoyama, Tomoaki Morioka, Katsuhito Mori, Shinya Fukumoto, Atsushi Shioi, Taro Shimono, Hisako Fujii, Daijiro Kabata, Ayumi Shintani, Masanori Emoto, Masaaki Inaba
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04515-w

Internet

https://doi.org/10.1038/s41598-017-04515-w

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