Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients

Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients

IntroductionOsteolytic bone metastasis in advanced breast cancer stages are a major complication for patient´s quality life and a sign of low survival prognosis. Permissive microenvironments which allow cancer cell secondary homing and later proliferation are fundamental for metastatic processes. Th...

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Bibliographic Details
Main Authors: Valeria Fernández Vallone, Francisco Raúl Borzone, Leandro Marcelo Martinez, María Belén Giorello, Hosoon Choi, Federico Dimase, Leonardo Feldman, Raúl Horacio Bordenave, Ana Marisa Chudzinski-Tavassi, Emilio Batagelj, Norma Alejandra Chasseing
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
pre-metastatic niche
bone metastasis
RANKL
CCL-2
spontaneous osteoclastogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1073793/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1073793/full

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