Biophysical features of MagA expression in mammalian cells: implications for MRI contrast

Biophysical features of MagA expression in mammalian cells: implications for MRI contrast

We compared overexpression of the magnetotactic bacterial gene MagA with the modified mammalian ferritin genes HF+LF, in which both heavy and light subunits lack iron response elements. Whereas both expression systems have been proposed for use in non-invasive, magnetic resonance (MR) reporter gene...

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Bibliographic Details
Main Authors: Anindita eSengupta, Karina eQuiaoit, R Terry Thompson, Frank S Prato, Neil eGelman, Donna E Goldhawk
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Microbiology
Subjects:
Iron
Magnetic Resonance Imaging
Cancer cells
MagA
modified ferritin subunits
relaxation rates
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00029/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00029/full

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