PCSK9 inhibitors ameliorate arterial stiffness in ACS patients: evidences from Mendelian randomization, a retrospective study and basic experiments

PCSK9 inhibitors ameliorate arterial stiffness in ACS patients: evidences from Mendelian randomization, a retrospective study and basic experiments

BackgroundCurrent evidences suggest that Proprotein Convertase Subtilisin/kexin Type 9 inhibitors (PCSK9i) exhibit a protective influence on acute coronary syndrome (ACS). Nevertheless, further investigation is required to comprehend the impact and mechanisms of these pharmaceutical agents on inflam...

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Bibliographic Details
Main Authors: Linghao Xu, Liang Wang, Yuanqi Wang, Yiqiong Wang, Yuanzhen Jiang, Peizhao Du, Jing Cheng, Chunsheng Zhang, Ruijie Wang, Tiantian Jiao, Lijian Xing, Jiangping Ma, Jiming Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Medicine
Subjects:
acute coronary syndromes
PCSK9 inhibitors
arterial stiffness
C-reactive protein
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1408760/full

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https://www.frontiersin.org/articles/10.3389/fmed.2024.1408760/full

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