Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates

Exosomes may mediate cell-to-cell communication by transporting various proteins and nucleic acids to neighboring cells. Some protein and RNA cargoes are significantly enriched in exosomes. How cells efficiently and selectively sort them into exosomes remains incompletely explored. Previously, we re...

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Bibliographic Details
Main Authors: Xiao-Man Liu, Liang Ma, Randy Schekman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/71982