Characterization of NAD+/NADP+-Specific Isocitrate Dehydrogenases From Oleaginous Fungus Mortierella alpina Involved in Lipid Accumulation

Characterization of NAD+/NADP+-Specific Isocitrate Dehydrogenases From Oleaginous Fungus Mortierella alpina Involved in Lipid Accumulation

Mortierella alpina has a strong capacity for lipid accumulation. Isocitrate dehydrogenase (IDH) plays an important role in affecting the flow of intracellular carbon sources and reducing power NADPH for lipid biosynthesis. In this study, the effect of various IDHs (NAD+- and NADP+-specific) in M. al...

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Bibliographic Details
Main Authors: Xin Tang, Xiaoqi Sun, Xuxu Wang, Hao Zhang, Yong Q. Chen, Jianxin Zhao, Haiqin Chen, Wei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Nutrition
Subjects:
Mortierella alpina
isocitrate dehydrogenase
homologous overexpression
lipid accumulation
mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.746342/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2021.746342/full

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