Genomic aberrations in the HTPAP promoter affect tumor metastasis and clinical prognosis of hepatocellular carcinoma.

We previously reported that the intronic tagSNP +357G/C in the metastasis suppressor HTPAP is associated with metastasis and prognosis of hepatocellular carcinoma (HCC). The aim of this study was to investigate whether SNPs in the HTPAP promoter modulate HTPAP expression and prognosis of HCC. Genomi...

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Bibliographic Details
Main Authors: Jin-Cai Wu, Hu-Liang Jia, Zhuo-Ri Li, Kai-Lun Zhou, Lun-Xiu Qin, Qiong-Zhu Dong, Ning Ren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946185?pdf=render