Cardioprotective Mechanisms of Interrupted Anesthetic Preconditioning with Sevoflurane in the Setting of Ischemia/Reperfusion Injury in Rats

Cardioprotective Mechanisms of Interrupted Anesthetic Preconditioning with Sevoflurane in the Setting of Ischemia/Reperfusion Injury in Rats

Background: Anesthetic preconditioning (AP) is known to mimic ischemic preconditioning. The purpose of this study was to investigate the effects of an interrupted sevoflurane administration protocol on myocardial ischemia/reperfusion (I/R) injury. Methods: Male Wistar rats (<i>n</i> = 60...

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Bibliographic Details
Main Authors: Mihaela Roxana Popescu, Bogdan Pavel, Gheorghita Isvoranu, Laura Cristina Ceafalan, Anca Maria Panaitescu, Ruxandra Irina Sava, Adelina Vlad, Leon Zagrean
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Applied Sciences
Subjects:
anesthetic preconditioning
sevoflurane
myocardial protection
ischemia/reperfusion injury
apoptosis
fibrosis
Online Access:https://www.mdpi.com/2076-3417/12/3/1476

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https://www.mdpi.com/2076-3417/12/3/1476

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