Activated microglia inhibit axonal growth through RGMa.

By causing damage to neural networks, spinal cord injuries (SCI) often result in severe motor and sensory dysfunction. Functional recovery requires axonal regrowth and regeneration of neural network, processes that are quite limited in the adult central nervous system (CNS). Previous work has shown...

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Bibliographic Details
Main Authors: Mari Kitayama, Masaki Ueno, Toru Itakura, Toshihide Yamashita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3177894?pdf=render