Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions
Abstract Interleukin-1α is a suggested dual-function cytokine that diverged from interleukin-1β in mammals potentially by acquiring additional biological roles that relate to highly conserved regions in the pro-domain of interleukin-1α, including a nuclear localisation sequence and histone acetyltra...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-50901-0 |