The AHR Signaling Attenuates Autoimmune Responses During the Development of Type 1 Diabetes

The AHR Signaling Attenuates Autoimmune Responses During the Development of Type 1 Diabetes

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcriptional factor widely expressed in immune cells. Its ligands range from xenobiotics and natural substances to metabolites, which renders it capable of sensing and responding to a variety of environmental cues. Although AHR signaling h...

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Bibliographic Details
Main Authors: Tiantian Yue, Fei Sun, Chunliang Yang, Faxi Wang, Jiahui Luo, Ping Yang, Fei Xiong, Shu Zhang, Qilin Yu, Cong-Yi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
aryl hydrocarbon receptor
T1D
immune response
AHR Ligands
therapeutic target
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01510/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01510/full

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