<i>Col1a2</i>-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics

<i>Col1a2</i>-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics

Rationale: The adult cardiac extracellular matrix (ECM) is largely comprised of type I collagen. In addition to serving as the primary structural support component of the cardiac ECM, type I collagen also provides an organizational platform for other ECM proteins, matricellular proteins, and signali...

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Bibliographic Details
Main Authors: Stephanie L. K. Bowers, Qinghang Meng, Yasuhide Kuwabara, Jiuzhou Huo, Rachel Minerath, Allen J. York, Michelle A. Sargent, Vikram Prasad, Anthony J. Saviola, David Ceja Galindo, Kirk C. Hansen, Ronald J. Vagnozzi, Katherine E. Yutzey, Jeffery D. Molkentin
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
type I collagen
cardiac hypertrophy
cardiomyocyte
fibroblast
extracellular matrix
Online Access:https://www.mdpi.com/2073-4409/12/17/2174

Internet

https://www.mdpi.com/2073-4409/12/17/2174

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