Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations

Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations

Summary: Alzheimer disease (AD) is the most common form of senile dementia, with high incidence late in life in many populations including Caribbean Hispanic (CH) populations. Such admixed populations, descended from more than one ancestral population, can present challenges for genetic studies, inc...

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Hlavní autoři: Andrea R.V.R. Horimoto, Lisa A. Boyken, Elizabeth E. Blue, Kelsey E. Grinde, Rafael A. Nafikov, Harkirat K. Sohi, Alejandro Q. Nato, Jr., Joshua C. Bis, Luis I. Brusco, Laura Morelli, Alfredo Ramirez, Maria Carolina Dalmasso, Seth Temple, Claudia Satizabal, Sharon R. Browning, Sudha Seshadri, Ellen M. Wijsman, Timothy A. Thornton
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2023-07-01
Edice:HGG Advances
Témata:
local ancestry
multi-ethnic
gene mapping
haplotype
protective
non-coding
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2666247723000398

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http://www.sciencedirect.com/science/article/pii/S2666247723000398

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